SCHEMBL8196834

SCHEMBL8196834

CC(NCCc1ccc(Cl)cc1Cl)c1ccc(Cl)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPK1 P28482 2/20 0.46
HTT P42858 2/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
ALDH1A1 P00352 1/20 0.45
CNR1 P21554 1/20 0.43
RAB9A P51151 1/20 0.43
POLB P06746 1/20 0.43
GPR84 Q9NQS5 1/20 0.43
METAP2 P50579 2/20 0.42
METAP1 P53582 2/20 0.42
HPGD P15428 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2D6 P10635 1/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14438295 0.83 MEN1 (0.57) MEN1KMT2AMAPK1HTTALDH1A1
SCHEMBL13137656 0.82 LMNA (0.50) MEN1KMT2AHTTLMNATP53
SCHEMBL13627131 0.78 LMNA (0.53) MEN1KMT2AHTTLMNATP53
SCHEMBL13267555 0.78 LMNA (0.53) MEN1KMT2AHTTLMNATP53
SCHEMBL680436 0.74 TAAR1 (0.60) MEN1KMT2AMAPK1HTTLMNA
SCHEMBL8210156 0.74 LMNA (0.67) MEN1KMT2AMAPK1HTTLMNA
SCHEMBL28650574 0.74 TAAR1 (0.55) MEN1KMT2AMAPK1HTTALDH1A1
SCHEMBL1436122 0.74 RAB9A (0.46) MEN1KMT2AHTTLMNATP53
SCHEMBL24762848 0.73 LMNA (0.47) MEN1KMT2AHTTLMNATP53
SCHEMBL13995332 0.73 MEN1 (0.53) MEN1KMT2AMAPK1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6093851-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-07-25 US disclosed