SCHEMBL8196995

SCHEMBL8196995

C=C(CP(=O)(OC)OC)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TET2 Q6N021 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10334291 0.82 ALDH1A1 (0.41) ALDH1A1EGLN1
SCHEMBL18196364 0.80 PGK1 (0.44) ALDH1A1TET2EGLN1
SCHEMBL28490986 0.80 TET2 (0.34) TET2
SCHEMBL11045567 0.74 PGK1 (0.46)
SCHEMBL19008260 0.74 ALDH1A1 (0.38) ALDH1A1EGLN1
SCHEMBL18393481 0.74 ALDH1A1 (0.33) ALDH1A1
SCHEMBL991 0.72 TSHR (0.46) ALDH1A1TET2
Phosphoric Acid SCHEMBL28171833 0.71 ALDH1A1 (0.42) ALDH1A1TET2EGLN1
SCHEMBL11870593 0.71 ALDH1A1 (0.38) ALDH1A1
SCHEMBL11042103 0.71 POLB (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3153186-B1 METHOD FOR PRODUCING AN ANTIBACTERIAL COATING COMPOSITION FOR IMPLANTS BRASSELER GMBH & CO KG GEB (DE) 2018-03-21 EP claimed
EP-0997455-A1 Restricted 9-cis retenoids American Cyanamid Company (US) 2000-05-03 EP disclosed
US-5968908-A Restricted 9-cis retinoids AMERICAN CYANAMID COMPANY (US) 1999-10-19 US disclosed
EP-0718285-A2 Restricted 9-cis-retinoids American Cyanamid Company (US) 1996-06-26 EP disclosed
US-5473092-A Synthesis of optically-active phosphono analogs of succinates MONSANTO COMPANY (US) 1995-12-05 US disclosed