Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 11/20 | 0.49 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569922 | 0.77 | PTGS2 (0.47) | CYP19A1 | |
| SCHEMBL7563098 | 0.75 | CYP17A1 (0.47) | CYP17A1CYP24A1CYP19A1 | |
| SCHEMBL8194804 | 0.74 | PTGDR2 (0.38) | — | |
| SCHEMBL15350420 | 0.70 | L3MBTL1 (0.48) | — | |
| SCHEMBL8194418 | 0.68 | CYP17A1 (0.67) | CYP17A1CYP24A1CYP19A1 | |
| SCHEMBL2338184 | 0.68 | ALDH1A1 (0.42) | — | |
| SCHEMBL7568529 | 0.67 | CYP17A1 (0.47) | CYP17A1CYP24A1CYP19A1CYP26A1 | |
| SCHEMBL8214431 | 0.67 | CYP17A1 (0.50) | CYP17A1CYP24A1CYP26A1 | |
| SCHEMBL7565140 | 0.67 | PTGS2 (0.45) | CYP19A1CYP26A1 | |
| SCHEMBL8185720 | 0.66 | CYP24A1 (0.52) | CYP17A1CYP24A1CYP19A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020611-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |