SCHEMBL819752

SCHEMBL819752

CC(C)COCC(C(=O)Cl)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 9/20 0.41
ALDH1A1 P00352 3/20 0.39
NPC1 O15118 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SLC22A2 O15244 1/20 0.36
SLC47A1 Q96FL8 1/20 0.36
MAPT P10636 1/20 0.35
P2RX7 Q99572 1/20 0.35
POLB P06746 1/20 0.35
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819517 0.85 EPHX2 (0.40) EPHX2ALDH1A1NPC1MEN1KMT2A
SCHEMBL888524 0.83 LMNA (0.39) EPHX2ALDH1A1NPC1MEN1KMT2A
SCHEMBL820119 0.81 ALDH1A1 (0.41) EPHX2ALDH1A1NPC1MEN1KMT2A
SCHEMBL28524736 0.72 EPHX2 (0.40) EPHX2ALDH1A1NPC1MEN1KMT2A
SCHEMBL888633 0.71 LMNA (0.42) EPHX2ALDH1A1NPC1MEN1KMT2A
SCHEMBL888450 0.70 ALDH1A1 (0.50) EPHX2ALDH1A1NPC1MEN1KMT2A
SCHEMBL4138799 0.69 NPC1 (0.50) EPHX2ALDH1A1NPC1MEN1KMT2A
SCHEMBL819751 0.68 HSD11B1 (0.33) EPHX2
SCHEMBL888273 0.67 ALDH1A1 (0.50) EPHX2ALDH1A1NPC1MEN1KMT2A
SCHEMBL26477718 0.66 CA12 (0.40) ALDH1A1MEN1KMT2ASLC22A2SLC47A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102250266-B Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO., LTD. (JP) 2014-10-22 CN disclosed
CN-103289210-A Polypropylene resin composition and molded body containing same SUMITOMO CHEMICAL CO 2013-09-11 CN disclosed
US-8288488-B2 Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
CN-102250266-A Process for producing solid catalyst component for olefin polymerization SUMITOMO CHEMICAL CO 2011-11-23 CN disclosed
US-20110269929-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed
US-20110269928-A1 PROCESS FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-03 US disclosed