Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MRE11 | P49959 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197809 | 1.00 | PIM1 (0.48) | PIM1NPC1PIK3CGPIK3CAPOLB | |
| SCHEMBL1248926 | 0.89 | PIM1 (0.62) | PIM1NPC1PIK3CGPIK3CAPOLB | |
| SCHEMBL1248927 | 0.89 | PIM1 (0.62) | PIM1NPC1PIK3CGPIK3CAPOLB | |
| SCHEMBL12891971 | 0.89 | PIM1 (0.62) | PIM1NPC1PIK3CGPIK3CAPOLB | |
| SCHEMBL8207353 | 0.85 | PIM1 (0.48) | PIM1NPC1PIK3CGPIK3CAASH1L | |
| SCHEMBL8207351 | 0.85 | PIM1 (0.48) | PIM1NPC1PIK3CGPIK3CAASH1L | |
| SCHEMBL8205587 | 0.76 | NPC1 (0.47) | NPC1MEN1KMT2AASH1LPARP1 | |
| SCHEMBL8205583 | 0.76 | NPC1 (0.47) | NPC1MEN1KMT2AASH1LPARP1 | |
| SCHEMBL8204792 | 0.76 | POLB (0.58) | PIM1NPC1PIK3CGPIK3CAPOLB | |
| SCHEMBL8204790 | 0.76 | POLB (0.58) | PIM1NPC1PIK3CGPIK3CAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |