Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 14/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | TOP2A | P11388 | 2/20 | 0.59 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771337 | 0.98 | NISCH (0.66) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL13030877 | 0.88 | NISCH (0.73) | NISCHTOP2ATOP2B | |
| SCHEMBL5476725 | 0.87 | NISCH (0.79) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL8198758 | 0.86 | NISCH (0.76) | NISCH | |
| SCHEMBL8201492 | 0.83 | NISCH (0.84) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL8141372 | 0.82 | NISCH (1.00) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL8197935 | 0.80 | NISCH (0.75) | NISCH | |
| SCHEMBL8202670 | 0.80 | NISCH (0.69) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL8188355 | 0.80 | LMNA (0.92) | NISCHLMNARECQLTOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL8196753 | 0.78 | TOP2A (0.55) | NISCHLMNARECQLTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |