Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 12/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | CASP1 | P29466 | 1/20 | 0.74 |
| ▸ | CASP7 | P55210 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | TOP2A | P11388 | 1/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105024 | 0.96 | NISCH (1.00) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| Bromide SCHEMBL29039569 | 0.94 | NISCH (0.96) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL28772851 | 0.94 | NISCH (0.96) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| Ammonia Solution, Strong SCHEMBL7104964 | 0.94 | NISCH (0.96) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL5476725 | 0.89 | NISCH (0.79) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL28515381 | 0.88 | NISCH (0.85) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL24495491 | 0.86 | NISCH (1.00) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| Alcohol SCHEMBL28563093 | 0.85 | NISCH (0.79) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL8195812 | 0.83 | NISCH (0.71) | NISCHALDH1A1CYP1A2HPGDCASP1 | |
| SCHEMBL11263510 | 0.83 | NISCH (0.71) | NISCHALDH1A1CYP1A2HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846688-B1 | New imidazoline derivatives having affinity for the imidazoline receptor | ADIR (FR) | 2000-02-16 | — | — | EP | claimed |
| EP-0846688-A1 | New imidazoline derivatives having affinity for the imidazoline receptor | ADIR ET COMPAGNIE (FR) | 1998-06-10 | — | — | EP | claimed |