Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352545 | 0.85 | PLA2G2A (0.38) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL8353085 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL8193378 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL8352756 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL8357808 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL8357815 | 0.80 | PLA2G2A (0.45) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL9863448 | 0.80 | TK1 (0.36) | ALDH1A1MCHR1LMNATK1CA2 | |
| SCHEMBL8347160 | 0.78 | PLA2G2C (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL8346912 | 0.78 | PLA2G2C (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL8352925 | 0.78 | PLA2G2C (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059906-A1 | AMINOHETEROCYCLE-SUBSTITUTED GLYCEROLS | CLARION PHARMACEUTICALS, INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| US-5891881-A | PROPANE 1,2,3-SUBSTITUTED WITH ONE OF EACH: ETHER OR SULFIDE GROUP; HYDROXY GROUP; AND AMINOHETEROCYCLIC GROUP; WOUND HEALING PROMOTER FOR MAMMALS | CLARION PHARMACEUTICALS INC. (US) | 1999-04-06 | — | — | US | disclosed |