SCHEMBL8353085

SCHEMBL8353085

CCCCCCCCCCCCCCCCOC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)COS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.49
PLA2G10 O15496 1/20 0.49
PLA2G1B P04054 1/20 0.49
PLA2G5 P39877 1/20 0.49
PLA2G2C Q5R387 1/20 0.39
MCHR1 Q99705 1/20 0.36
TK2 O00142 7/20 0.35
TK1 P04183 1/20 0.33
CNR2 P34972 1/20 0.33
STAT3 P40763 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8357808 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C
SCHEMBL8352756 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C
SCHEMBL8193378 1.00 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C
SCHEMBL8357815 0.94 PLA2G2A (0.45) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C
SCHEMBL8741371 0.85 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5TK2
SCHEMBL8197988 0.85 PLA2G2A (0.35) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C
SCHEMBL8347160 0.84 PLA2G2C (0.46) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C
SCHEMBL8346912 0.84 PLA2G2C (0.46) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C
SCHEMBL8352925 0.84 PLA2G2C (0.46) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C
SCHEMBL8352304 0.84 PLA2G2C (0.46) PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5972982-A CONTAINING 5-TO 9-MEMBERED HETEROARYL MONO- OR BICYCLIC RING SYSTEM HAVING NO MORE THAN 1 CARBONYL CARBON IN THE RING SYSTEM; VIRICIDES, BACTERICIDES CLARION PHARMACEUTICALS INC. (US) 1999-10-26 US disclosed