Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498755 | 0.81 | MIF (0.67) | TSHRMAOBMAOAKDM4EHSD17B10 | |
| SCHEMBL2385579 | 0.80 | GPR35 (0.59) | CYP2C19TSHRMAOBMAOAHTT | |
| SCHEMBL12611203 | 0.80 | LMNA (0.70) | LMNACYP2C19TSHRMAOBMAOA | |
| SCHEMBL5905805 | 0.80 | MAOB (0.73) | LMNACYP2C19TSHRMAOBMAOA | |
| SCHEMBL13561369 | 0.79 | LMNA (1.00) | LMNACYP2C19TSHRMAOBMAOA | |
| SCHEMBL11391760 | 0.78 | KDM4E (0.63) | CYP2C19MAOBMAOAHTTKDM4E | |
| SCHEMBL5905811 | 0.76 | CYP2C19 (1.00) | LMNACYP2C19TSHRMAOBMAOA | |
| SCHEMBL8936325 | 0.76 | MAOA (0.56) | CYP2C19MAOBMAOAHTTKDM4E | |
| SCHEMBL3065914 | 0.76 | TSHR (0.71) | LMNACYP2C19TSHRMAOAHTT | |
| SCHEMBL12651748 | 0.75 | MEN1 (0.74) | LMNACYP2C19TSHRMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000075125-A1 | NONINVASIVE IMAGING OF NUCLEIC ACID VECTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2000-12-14 | — | — | WO | disclosed |