SCHEMBL8198544

SCHEMBL8198544

Cl[SiH2]CC(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
HTR6 P50406 1/20 0.35
SIGMAR1 Q99720 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4651680 0.79 KDM4E (0.33) HTR2AHTR6SIGMAR1
SCHEMBL7927919 0.78 HTR2A (0.35) HTR2AHTR6SIGMAR1
SCHEMBL9145117 0.78 HTR6 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL9146462 0.78 HTR6 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL6673086 0.77 HTR2A (0.36) HTR2AHTR6SIGMAR1
SCHEMBL1921591 0.77 HTR2A (0.38) HTR2AHTR6SIGMAR1
SCHEMBL3383301 0.77 HTR2A (0.38) HTR2AHTR6SIGMAR1
SCHEMBL3383305 0.77 HTR2A (0.38) HTR2AHTR6SIGMAR1
SCHEMBL6904136 0.76 HTR6 (0.38) HTR2AHTR6SIGMAR1
SCHEMBL9860034 0.75 HTR2A (0.37) HTR2AHTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6111040-A Process for the production of olefinic polymers NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-08-29 US disclosed
EP-0745616-B1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO LTD (JP) 1999-04-07 EP disclosed
US-5795839-A COORDINATION POLYMERIZATION CATALYST FOR POLYOLEFIN MANUFACTURE NIPPON OIL CO., LTD. (JP) 1998-08-18 US disclosed
US-5750454-A Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0546690-B1 Catalyst components for polymerization of olefins NIPPON OIL CO LTD (JP) 1998-03-04 EP disclosed
US-5707914-A ZIRCONIUM OR HAFNIUM ALKYLS OR ALKOXIDES NIPPON OIL CO., LTD. (JP) 1998-01-13 US disclosed
US-5677401-A COORDINATION CATALYST NIPPON OIL CO., LTD. (JP) 1997-10-14 US disclosed
US-5625014-A Method for polymerization of olefins NIPPON OIL CO., LTD. (JP) 1997-04-29 US disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0748823-A1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO. LTD. (JP) 1996-12-18 EP disclosed
EP-0745616-A1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO. LTD. (JP) 1996-12-04 EP disclosed
US-5331071-A Transition metal and alumoxane components NIPPON OIL CO., LTD. (JP) 1994-07-19 US disclosed
EP-0546690-A1 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1993-06-16 EP disclosed