SCHEMBL8198697

SCHEMBL8198697

O=C(O)C(CCc1cccc(N2C(=O)C=CC2=O)c1)N1C(=O)CCC1=O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
PKM P14618 3/20 0.52
MGLL Q99685 10/20 0.48
HTT P42858 2/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
XBP1 P17861 1/20 0.44
MAPK1 P28482 1/20 0.44
CCR6 P51684 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
FAAH O00519 4/20 0.43
HSP90AA1 P07900 2/20 0.43
ATM Q13315 1/20 0.43
KMT2A Q03164 2/20 0.42
NR1H3 Q13133 1/20 0.40
PARP1 P09874 1/20 0.37
DPP8 Q6V1X1 1/20 0.37
SLC1A2 P43004 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL326688 0.86 PKM (0.49) ALDH1A1PKMMGLLHTTHPGD
SCHEMBL2169006 0.79 ALDH1A1 (0.50) ALDH1A1PKMMGLLHTTHPGD
SCHEMBL26623027 0.76 ALDH1A1 (0.67) ALDH1A1PKMMGLLMAPK1NPSR1
SCHEMBL1824376 0.74 DNMT1 (0.48) ALDH1A1PKMMGLLHPGDMAPK1
SCHEMBL28882413 0.73 HSP90AA1 (0.43) ALDH1A1PKMMGLLHTTMAPT
SCHEMBL23327953 0.72 ALDH1A1 (0.54) ALDH1A1PKMHPGDMAPK1SLC1A2
SCHEMBL8198691 0.71 MGLL (0.46) ALDH1A1PKMMGLLHTTMAPT
SCHEMBL11030538 0.71 KMT2A (0.53) ALDH1A1PKMMGLLHTTMAPT
SCHEMBL28019598 0.71 ALDH1A1 (0.49) ALDH1A1PKMMAPTHPGDMAPK1
SCHEMBL19508684 0.71 MGLL (0.58) ALDH1A1PKMMGLLHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015872-A2 APPARATUS AND METHOD FOR DETECTING AND IDENTIFYING INFECTIOUS AGENTS Prolume, Ltd. (US) 2000-07-05 EP disclosed
WO-1998026277-A2 APPARATUS AND METHOD FOR DETECTING AND IDENTIFYING INFECTIOUS AGENTS PROLUME, LTD. (US) 1998-06-18 WO disclosed