Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362453 | 0.80 | PRMT1 (0.68) | NISCHPRMT3EHMT2PRMT6PRMT1 | |
| Hydrochloric Acid SCHEMBL3383477 | 0.79 | PRMT1 (0.66) | NISCHPRMT3EHMT2PRMT6PRMT1 | |
| SCHEMBL7662705 | 0.79 | KMT2A (0.79) | LMNAKDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL8238119 | 0.79 | PRMT1 (0.69) | NISCHPRMT3EHMT2PRMT6PRMT1 | |
| SCHEMBL523059 | 0.77 | LMNA (0.96) | LMNARECQLNISCH | |
| SCHEMBL8188355 | 0.76 | LMNA (0.92) | LMNARECQLNISCH | |
| Hydrochloric Acid SCHEMBL6785326 | 0.75 | PRMT1 (0.47) | LMNARECQLNISCHPRMT3EHMT2 | |
| SCHEMBL14854511 | 0.75 | PRMT1 (0.58) | NISCHPRMT3EHMT2PRMT6PRMT1 | |
| SCHEMBL8229714 | 0.74 | PRMT1 (0.71) | NISCHPRMT3EHMT2PRMT6PRMT1 | |
| SCHEMBL13204586 | 0.74 | PRMT1 (0.62) | NISCHPRMT3EHMT2PRMT6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |