Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17681578 | 1.00 | CASP3 (0.42) | CASP3SENP8SENP7SENP6CCNB2 | |
| SCHEMBL17681580 | 0.86 | GCGR (0.41) | TLR8 | |
| SCHEMBL10614683 | 0.83 | RAB9A (0.36) | MAPTTLR8ALDH1A1HPGDNPC1 | |
| SCHEMBL8198894 | 0.83 | ESR1 (0.41) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL2319620 | 0.82 | MAPT (0.43) | MAPTTLR8MGLLALDH1A1NPC1 | |
| SCHEMBL2314604 | 0.81 | RARB (0.51) | MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2310945 | 0.81 | RARB (0.51) | MAPTALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5534014 | 0.79 | ME2 (0.42) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL10717982 | 0.78 | MAPT (0.47) | MAPTMGLLALDH1A1HPGDNPC1 | |
| SCHEMBL3474362 | 0.78 | MAPT (0.47) | MAPTMGLLALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315510-B2 | Method and application of unsymmetrically meso-substituted porphyrins and chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2016-04-19 | — | — | US | claimed |