Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 9/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025063 | 0.78 | CA12 (0.47) | GPR35MAOAALDH1A1HPGDCYP2A6 | |
| SCHEMBL7027354 | 0.76 | GPR35 (0.38) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL16795823 | 0.72 | CYP17A1 (0.48) | GPR35MAOBPTPN1MAOAALDH1A1 | |
| SCHEMBL1992120 | 0.72 | CYP2A6 (0.62) | GPR35PTPN1MAOAALDH1A1HPGD | |
| SCHEMBL1367003 | 0.72 | GPR35 (0.79) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL28572283 | 0.71 | GPR35 (1.00) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL3080344 | 0.71 | GPR35 (1.00) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL30110196 | 0.70 | MAOB (1.00) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL17037289 | 0.70 | MAOB (1.00) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL30110368 | 0.70 | GPR35 (0.74) | GPR35MAOBMAOAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133305-A | PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED DISORDERS SUCH AS CANCER | SUGEN, INC. (US) | 2000-10-17 | — | — | US | disclosed |