Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247705 | 0.95 | JAK3 (0.39) | GRIN2BGRIN2CCTSKJAK3USP2 | |
| SCHEMBL15425362 | 0.81 | GRIN2B (0.41) | GRIN2BGRIN2CCTSKJAK3USP2 | |
| SCHEMBL705582 | 0.81 | GRIN2B (0.41) | GRIN2BGRIN2CCTSKJAK3USP2 | |
| SCHEMBL8950858 | 0.81 | GRIN2B (0.41) | GRIN2BGRIN2CCTSKJAK3USP2 | |
| SCHEMBL9580752 | 0.80 | L3MBTL1 (0.37) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL14669188 | 0.80 | JAK3 (0.45) | GRIN2BGRIN2CCTSKJAK3USP2 | |
| SCHEMBL28389036 | 0.79 | GRIN2B (0.40) | GRIN2BGRIN2CCTSKJAK3USP2 | |
| SCHEMBL28858349 | 0.79 | GRIN2B (0.40) | GRIN2BGRIN2CCTSKJAK3USP2 | |
| SCHEMBL70812 | 0.79 | GRIN2B (0.40) | GRIN2BGRIN2CCTSKJAK3USP2 | |
| SCHEMBL28389038 | 0.79 | GRIN2B (0.40) | GRIN2BGRIN2CCTSKJAK3USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |