Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199036 | 0.80 | GRIN2B (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7435072 | 0.77 | TSHR (0.39) | L3MBTL1TSHRPOLBALDH1A1HTT | |
| SCHEMBL73672 | 0.76 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4810806 | 0.76 | — | — | |
| SCHEMBL4247705 | 0.76 | JAK3 (0.39) | SMN1; SMN2 | |
| SCHEMBL28912922 | 0.75 | TSHR (0.38) | L3MBTL1TSHRPOLBALDH1A1HTT | |
| SCHEMBL27373455 | 0.73 | TSHR (0.39) | L3MBTL1TSHRPOLBALDH1A1HTT | |
| SCHEMBL15260667 | 0.72 | TSHR (0.36) | L3MBTL1TSHRPOLBALDH1A1HTT | |
| SCHEMBL31520536 | 0.72 | TSHR (0.36) | L3MBTL1TSHRPOLBALDH1A1HTT | |
| SCHEMBL15260668 | 0.72 | OPRM1 (0.37) | TSHRPOLBALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210202-A | Chiral phosphorous compounds, a process for their manufacture and their application to the catalysis of enantioselective synthesis reactions | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1993-05-11 | — | — | US | disclosed |
| US-5099077-A | Dihydrocarbylphosphioxy substituted groups with amine or phosphinoamines as ligands | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1992-03-24 | — | — | US | disclosed |
| US-4877908-A | Chiral phosphorus compounds, a process for their manufacture and their application to the catalysis of enantioselective synthesis reactions | NORSOLOR (FR) | 1989-10-31 | — | — | US | disclosed |
| EP-0136210-B1 | CHIRAL PHOSPHORUS LIGANDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE CATALYSIS OF ENANTIOSELECTIVE SYNTHESIS REACTIONS | NORSOLOR S.A. (FR) | 1989-08-16 | — | — | EP | disclosed |
| EP-0136210-A1 | Chiral phosphorus ligands, process for their preparation and their use in the catalysis of enantioselective synthesis reactions | NORSOLOR S.A. (FR) | 1985-04-03 | — | — | EP | disclosed |