Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209552 | 1.00 | LMNA (0.38) | LMNAMEN1ALDH1A1MAPTHTT | |
| SCHEMBL7206578 | 0.87 | LMNA (0.51) | LMNAMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8194004 | 0.87 | LMNA (0.51) | LMNAMEN1ALDH1A1MAPTHTT | |
| SCHEMBL3817265 | 0.84 | LMNA (0.46) | LMNAALDH1A1MAPTADORA3 | |
| SCHEMBL7210256 | 0.83 | NAAA (0.46) | LMNA | |
| SCHEMBL8193476 | 0.83 | NAAA (0.46) | LMNA | |
| SCHEMBL3817191 | 0.82 | LMNA (0.51) | LMNAALDH1A1MAPTADORA3 | |
| SCHEMBL7209654 | 0.82 | LMNA (0.49) | LMNAALDH1A1MAPT | |
| SCHEMBL8193747 | 0.82 | LMNA (0.49) | LMNAALDH1A1MAPT | |
| SCHEMBL8192660 | 0.81 | LMNA (0.42) | LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |