Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192707 | 0.75 | — | — | |
| SCHEMBL6169570 | 0.72 | CHRNB2 (0.51) | CHRNB2CHRNA7CHRNA4CYP2A6 | |
| SCHEMBL7429484 | 0.71 | CHRNB2 (0.40) | CHRNB2CHRNA7CHRNA4CYP2A6 | |
| SCHEMBL8193763 | 0.67 | MAPT (0.41) | — | |
| SCHEMBL27612309 | 0.65 | NOTUM (0.32) | — | |
| SCHEMBL105810 | 0.63 | HRH4 (0.39) | — | |
| SCHEMBL28325864 | 0.62 | KDM1A (0.34) | CYP2A6 | |
| SCHEMBL18284951 | 0.60 | CHRNB2 (0.53) | CHRNB2CHRNA7CHRNA4CYP2A6 | |
| SCHEMBL5607050 | 0.60 | CHRNB2 (0.38) | CHRNB2CHRNA7CHRNA4CYP2A6 | |
| SCHEMBL196791 | 0.59 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |