SCHEMBL196791

SCHEMBL196791

[c]1ccc(-c2cc[c]cn2)nc1

nearest known ligand 0.30

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30
CCR1 P32246 1/20 0.30
CCR5 P51681 1/20 0.30
CCR8 P51685 1/20 0.30
METAP1 P53582 1/20 0.30
BLM P54132 1/20 0.30
HIF1A Q16665 1/20 0.30
DOHH Q9BU89 1/20 0.30
P4HTM Q9NXG6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4894768 0.85 CCR1 (0.48) KDM4ELMNACYP1A2POLBCCR1
SCHEMBL1047005 0.83 KDM4E (0.61) KDM4ELMNACYP1A2POLBCCR1
SCHEMBL17701188 0.80 SCN9A (0.31)
SCHEMBL3145603 0.80 KDM4A (0.38) KDM4ECYP1A2METAP1HIF1A
SCHEMBL69777 0.80 KMT2A (0.41)
SCHEMBL1315590 0.78 MAPT (0.42) KDM4ELMNACYP1A2
SCHEMBL18421817 0.77 GRM5 (0.44) KDM4ELMNACYP1A2
SCHEMBL2750109 0.77 NR4A2 (0.32) LMNACYP1A2
SCHEMBL2753969 0.77 ALOX5AP (0.32)
SCHEMBL2753948 0.77 HTR7 (0.36) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110118411-A1 POLYMERIC COMPOUND HAVING RESIDUE OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-19 US claimed
EP-2275469-A1 POLYMERIC COMPOUND HAVING RESIDUE OF NITROGENATED HETEROCYCLIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-01-19 EP claimed
JP-4093332-A None JP disclosed
US-20240251665-A1 TRANSVERSE CURRENT SUPPRESSING MATERIAL, CARBAZOLE COMPOUND, HOLE-INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT TOSOH CORPORATION (JP) 2024-07-25 US disclosed
CN-118355011-A Organic molecules for optoelectronic devices 三星显示有限公司 2024-07-16 CN disclosed
CN-118215668-A Organic molecules for optoelectronic devices 三星显示有限公司 2024-06-18 CN disclosed
CN-118201937-A Organic molecules for optoelectronic devices 三星显示有限公司 2024-06-14 CN disclosed
CN-117999266-A Organic molecules for optoelectronic devices 三星显示有限公司 2024-05-07 CN disclosed
CN-117980311-A Organic molecules for optoelectronic devices 三星显示有限公司 2024-05-03 CN disclosed
CN-117916247-A Organic molecules for optoelectronic devices 三星显示有限公司 2024-04-19 CN disclosed
CN-117897390-A Organic molecules for optoelectronic devices 三星显示有限公司 2024-04-16 CN disclosed
US-20080045493-A1 Heterocyclic Compounds Suitable For Treating Disorders That Respond To Modulation Of The Dopamine D3 Receptor ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2008-02-21 US disclosed
EP-1814849-A1 HETEROCYCLIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR Abbott GmbH & Co. KG (DE) 2007-08-08 EP disclosed
WO-2006040182-A1 HETEROCYCLIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR ABBOTT GMBH & CO. KG (DE) 2006-04-20 WO disclosed
US-6114498-A Benzobisazole polymers containing 2,2'-bipyridine-5,5 '-diyl moieties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2000-09-05 US disclosed
US-6114498-A Benzobisazole polymers containing 2,2'-bipyridine-5,5 '-diyl moieties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2000-09-05 US disclosed
US-6114498-A Benzobisazole polymers containing 2,2'-bipyridine-5,5 '-diyl moieties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2000-09-05 US disclosed
US-5424381-A Alkyl-substituted poly(2,2'-bipyridine-5,5'-diyl) and use thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 1995-06-13 US disclosed
JP-H0493332-A ORIENTATION FILM YAMAMOTO RYUICHI 1992-03-26 JP disclosed
JP-H00493332-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045493-A1 Heterocyclic Compounds Suitable For Treating Disorders That Respond To Modulation Of The Dopamine D3 Receptor DRD3, MC3R, CHRNA3 KDM4E 4368/4885LMNA 3510/4885CYP1A2 854/4885
US-20240251665-A1 TRANSVERSE CURRENT SUPPRESSING MATERIAL, CARBAZOLE COMPOUND, HOLE-INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT AXIN2, FZD7, SLC39A3 KDM4E 3963/4885LMNA 2480/4885CYP1A2 279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.