Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723832 | 0.79 | HTR7 (0.42) | PPARGSCN1ASCN2ASCN3AHTR7 | |
| SCHEMBL14102679 | 0.79 | SCN1A (0.45) | PPARGSCN1ASCN2ASCN3AHTR7 | |
| SCHEMBL3022750 | 0.78 | POLB (0.44) | PPARGSCN1ASCN2ASCN3AHTR7 | |
| SCHEMBL2858049 | 0.78 | HTR7 (0.41) | PPARGSCN1ASCN2ASCN3AHTR7 | |
| SCHEMBL13634421 | 0.77 | PPARG (0.41) | PPARGSCN1ASCN2ASCN3AHTR7 | |
| SCHEMBL4724796 | 0.76 | PPARG (0.40) | PPARGSCN1ASCN2ASCN3AHTR7 | |
| SCHEMBL3573088 | 0.76 | CHI3L1 (0.41) | PPARGSCN1ASCN2ASCN3AHTR7 | |
| SCHEMBL2861043 | 0.75 | PPARG (0.39) | PPARGSCN1ASCN2ASCN3AHTR7 | |
| SCHEMBL173416 | 0.75 | — | — | |
| SCHEMBL259464 | 0.74 | LMNA (0.50) | PPARGHSD17B10KDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |