Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199247 | 0.90 | AGTR2 (0.42) | CHRM2CHRM3ADRB2CHRM4ADRB1 | |
| SCHEMBL8199092 | 0.89 | KMT2A (0.40) | AOC3CHRM2CHRM3ADRB2CHRM4 | |
| SCHEMBL8211307 | 0.85 | CHRM5 (0.40) | CHRM2CHRM3ADRB2CHRM4ADRB1 | |
| SCHEMBL8206274 | 0.84 | SLC18A3 (0.43) | SIGMAR1ALDH1A1AGTR2 | |
| SCHEMBL8209743 | 0.84 | SLC18A3 (0.43) | SIGMAR1ALDH1A1AGTR2 | |
| SCHEMBL8209731 | 0.84 | HRH1 (0.39) | CHRM2CHRM3ADRB2CHRM4ADRB1 | |
| SCHEMBL8199191 | 0.84 | CHRM2 (0.38) | CHRM2CHRM3ADRB2CHRM4ADRB1 | |
| Hydrochloric Acid SCHEMBL8209836 | 0.83 | AGTR2 (0.47) | AOC3OPRM1OPRK1AGTR2 | |
| SCHEMBL8205248 | 0.83 | SLC18A3 (0.45) | OPRM1OPRK1SIGMAR1ALDH1A1AGTR2 | |
| SCHEMBL8205356 | 0.83 | CHIT1 (0.41) | CHRM2CHRM3ADRB2CHRM4ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | claimed |
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |