Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206274 | 0.99 | SLC18A3 (0.43) | SLC18A3SIGMAR1L3MBTL1AGTR2ALDH1A1 | |
| SCHEMBL8209743 | 0.99 | SLC18A3 (0.43) | SLC18A3SIGMAR1L3MBTL1AGTR2ALDH1A1 | |
| SCHEMBL8206587 | 0.93 | SLC18A3 (0.47) | SLC18A3AGTR2GRIN2BOPRM1OPRK1 | |
| SCHEMBL8199247 | 0.93 | AGTR2 (0.42) | SLC18A3SIGMAR1L3MBTL1AGTR2GRIN2B | |
| SCHEMBL8208772 | 0.91 | CHRM3 (0.45) | L3MBTL1CACNA1COPRM1POLB | |
| SCHEMBL8206924 | 0.87 | AGTR2 (0.43) | SLC18A3SIGMAR1AGTR2ALDH1A1GRIN2B | |
| SCHEMBL8209731 | 0.87 | HRH1 (0.39) | SLC18A3L3MBTL1AGTR2GRIN2BOPRM1 | |
| SCHEMBL8199191 | 0.87 | CHRM2 (0.38) | SLC18A3SIGMAR1L3MBTL1AGTR2CACNA1C | |
| Hydrochloric Acid SCHEMBL8209836 | 0.87 | AGTR2 (0.47) | SLC18A3AGTR2GRIN2BOPRM1OPRK1 | |
| SCHEMBL8205356 | 0.86 | CHIT1 (0.41) | SLC18A3AGTR2CACNA1COPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |