Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957829 | 0.83 | LMNA (0.38) | TYMPLMNA | |
| SCHEMBL6949843 | 0.83 | LTB4R (0.50) | LTB4RALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL6946482 | 0.81 | PARP1 (0.41) | TAAR1HPGDTSHR | |
| SCHEMBL6949338 | 0.80 | HRH3 (0.41) | HRH3TYMPMEN1KMT2A | |
| SCHEMBL12002490 | 0.67 | HDAC8 (0.46) | HRH3HTR1DEPHX2TAAR1TSHR | |
| SCHEMBL11376007 | 0.67 | LTA4H (0.46) | LTB4RALDH1A1APOBEC3GLMNAMEN1 | |
| SCHEMBL11281110 | 0.66 | HRH3 (0.39) | HRH3HTR1DALDH1A1APOBEC3GEPHX2 | |
| SCHEMBL104349 | 0.64 | — | — | |
| SCHEMBL3334615 | 0.63 | CYP2A6 (0.57) | HRH3HTR1DALDH1A1EPHX2TAAR1 | |
| SCHEMBL8124411 | 0.63 | HRH3 (0.44) | HRH3HTR1DTYMPEPHX2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000001674-A1 | PROCESS FOR MAKING 1,5-DISUBSTITUTED IMIDAZOLES | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | disclosed |