Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966780 | 0.79 | CA1 (0.52) | ALDH1A1MAPTGAATDP1CYP2C9 | |
| SCHEMBL13144225 | 0.73 | NPC1 (0.44) | ALDH1A1MAPTLMNAGAATDP1 | |
| SCHEMBL29498862 | 0.72 | RAB9A (0.45) | ALDH1A1MAPTLMNAGAATDP1 | |
| SCHEMBL29498865 | 0.70 | HSP90AA1 (0.41) | ALDH1A1MAPTLMNATDP1RAB9A | |
| SCHEMBL29498870 | 0.70 | RXRA (0.42) | MAPTLMNAGAATDP1RAB9A | |
| SCHEMBL17037473 | 0.69 | MAPT (0.50) | ALDH1A1MAPTGAATDP1CYP2C9 | |
| SCHEMBL6676922 | 0.69 | TDP1 (0.44) | ALDH1A1MAPTLMNAGAATDP1 | |
| SCHEMBL31758293 | 0.68 | RXRA (0.73) | ABCB11 | |
| SCHEMBL2594347 | 0.68 | RXRA (0.73) | ABCB11 | |
| SCHEMBL14966752 | 0.68 | CYP4A11 (0.51) | ALDH1A1MAPTLMNATDP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999063983-A9 | MULTIBINDING AGENTS THAT MODULATE PPARη AND RXR RECEPTORS | ADVANCED MEDICINE INC (US) | 2000-03-23 | — | — | WO | disclosed |