Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679871 | 0.84 | RXRA (0.59) | RXRAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31758293 | 0.77 | RXRA (0.73) | RXRAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2594347 | 0.77 | RXRA (0.73) | RXRAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24055389 | 0.73 | RXRA (0.67) | RXRAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8199065 | 0.71 | TDP1 (0.42) | TDP1RXRAHDAC3HDAC4HDAC1 | |
| SCHEMBL6908235 | 0.70 | RXRA (0.74) | TDP1RXRAHDAC3HDAC4HDAC1 | |
| SCHEMBL6693435 | 0.69 | RXRA (0.62) | RXRARXRBRXRGMEN1CYP26A1 | |
| SCHEMBL6675847 | 0.69 | RXRA (0.50) | RXRARXRBRXRGMEN1CYP26A1 | |
| Ethylene SCHEMBL8070484 | 0.67 | CA1 (0.73) | TDP1MEN1KMT2ACA1CA2 | |
| SCHEMBL2655292 | 0.67 | MEN1 (0.52) | TDP1MEN1NR4A2KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048390-A1 | SILICON COMPOUNDS | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004048391-A1 | SILICON COMPOUNDS TO BE USED AS LIGANDS FOR RETINOID RECEPTORS | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-10 | — | — | WO | disclosed |