Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497097 | 0.98 | MCHR1 (0.48) | MCHR1HTR2CRIPK1CNR1CNR2 | |
| SCHEMBL3067135 | 0.91 | RIPK1 (0.53) | MCHR1HTR2CRIPK1SLC6A4 | |
| SCHEMBL9370895 | 0.79 | MCHR1 (0.56) | MCHR1HTR2CRIPK1CNR1CNR2 | |
| SCHEMBL5673940 | 0.79 | ALDH1A1 (0.59) | MCHR1HTR2CRIPK1CNR1CNR2 | |
| SCHEMBL28729860 | 0.79 | MCHR1 (0.49) | MCHR1HTR2CRIPK1CNR1CNR2 | |
| SCHEMBL79139 | 0.79 | GAA (0.50) | MCHR1HTR2CRIPK1CNR1CNR2 | |
| SCHEMBL34475634 | 0.79 | MCHR1 (0.49) | MCHR1HTR2CRIPK1CNR1CNR2 | |
| SCHEMBL5777914 | 0.79 | LMNA (0.50) | MCHR1HTR2CRIPK1CNR1CNR2 | |
| SCHEMBL1988972 | 0.78 | SRC (0.46) | MCHR1HTR2CRIPK1CNR1CNR2 | |
| SCHEMBL14950871 | 0.78 | MCHR1 (0.55) | MCHR1HTR2CRIPK1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687686-B1 | AUREOBASIDINS | TAKARA SHUZO CO (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0687686-B1 | AUREOBASIDINS | TAKARA SHUZO CO (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0687686-A4 | AUREOBASIDINS | TAKARA SHUZO CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5698670-A | FUNGICIDES | TAKARA SHUZO CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5698670-A | FUNGICIDES | TAKARA SHUZO CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0687686-A1 | AUREOBASIDINS | TAKARA SHUZO CO. LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |
| EP-0687686-A1 | AUREOBASIDINS | TAKARA SHUZO CO. LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |
| WO-1995018147-A1 | AUREOBASIDINS | TAKARA SHUZO CO., LTD. (JP) | 1995-07-06 | — | — | WO | disclosed |