Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.44 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.41 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192695 | 0.87 | THRA (0.49) | THRATHRBCYP26A1SGPL1S1PR1 | |
| SCHEMBL18052663 | 0.82 | THRA (0.53) | THRATHRBCYP26A1SGPL1S1PR1 | |
| SCHEMBL8205603 | 0.81 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL15954358 | 0.81 | THRA (0.52) | THRATHRBCYP26A1SGPL1S1PR1 | |
| SCHEMBL15954361 | 0.81 | THRA (0.52) | THRATHRBCYP26A1SGPL1S1PR1 | |
| SCHEMBL8192821 | 0.81 | THRA (0.42) | THRATHRBSGPL1S1PR1ITGB3 | |
| SCHEMBL8809427 | 0.80 | TP53 (0.43) | THRATHRBRARBTP53TSHR | |
| SCHEMBL8591151 | 0.78 | CYP24A1 (0.42) | THRATHRBCYP26A1SGPL1S1PR1 | |
| SCHEMBL27919093 | 0.78 | CYP19A1 (0.56) | THRATHRBCYP19A1TP53 | |
| SCHEMBL8199839 | 0.77 | MLYCD (0.45) | THRATHRBSGPL1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | disclosed |