Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19221186 | 0.92 | MAOA (0.48) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL4723773 | 0.83 | MAOA (0.48) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL23355868 | 0.81 | KMT2A (0.46) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL9778992 | 0.80 | KDM1A (0.46) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL11384551 | 0.80 | KDM1A (0.46) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL29950610 | 0.80 | KDM1A (0.46) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL8155961 | 0.78 | ESR2 (0.45) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL13604657 | 0.78 | KDM1A (0.44) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL13558667 | 0.77 | NPC1 (0.59) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL529044 | 0.77 | SLC6A2 (0.45) | MAOAKDM1AMAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059501-A1 | WATER-SOLUBLE TRIOXANES AS POTENT AND SAFE ANTIMALARIAL AGENTS | JOHNS HOPKINS UNIVERSITY (US) | 2000-10-12 | — | — | WO | disclosed |