Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155961 | 0.94 | ESR2 (0.45) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL9778992 | 0.92 | KDM1A (0.46) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL29950610 | 0.92 | KDM1A (0.46) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL31165268 | 0.89 | MAPT (0.59) | MAOAKDM1AMAOBNPC1RAB9A | |
| SCHEMBL9778655 | 0.89 | KDM4E (0.44) | MAOAKDM1AMAOBMAPTDRD2 | |
| SCHEMBL19221186 | 0.87 | MAOA (0.48) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL11384551 | 0.83 | KDM1A (0.46) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL8200366 | 0.83 | MAOA (0.46) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL10452473 | 0.83 | NPC1 (0.54) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL9779134 | 0.82 | KDM4E (0.45) | MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |
| US-9585382-B2 | Composition comprising a pesticide and an acetal solvent | BASF SE (DE) | 2017-03-07 | — | — | US | disclosed |
| US-9585382-B2 | Composition comprising a pesticide and an acetal solvent | BASF SE (DE) | 2017-03-07 | — | — | US | disclosed |
| EP-3130587-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF Corporation (JP) | 2017-02-15 | — | — | EP | disclosed |
| WO-2016159071-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | 日油株式会社 | 2016-10-06 | — | — | WO | disclosed |
| US-20150232616-A1 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS | INTEZYNE TECHNOLOGIES, INC. | 2015-08-20 | — | — | US | disclosed |
| EP-2701502-B1 | COMPOSITION COMPRISING A PESTICIDE AND AN ACETALIC SOLVENT | BASF SE (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-8980326-B2 | Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents | INTEZYNE TECHNOLOGIES, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8779008-B2 | Polymeric micelles for drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| EP-1807436-B1 | HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) AND USES THEREOF | INTEZYNE TECHNOLOGIES INC (US) | 2014-06-18 | — | — | EP | disclosed |
| US-20110021718-A1 | SYNTHESIS OF HYBRID BLOCK COPOLYMERS AND USES THEREOF | INTEZYNE TECHNOLOGIES (US) | 2011-01-27 | — | — | US | disclosed |
| US-20100075260-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100075260-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20080176857-A1 | 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC. | 2008-07-24 | — | — | US | disclosed |
| EP-1874780-A1 | 4-PIPERAZINYLTHIENO[2,3-D]PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006100591-A1 | 4-PIPERAZINNYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
| EP-0210518-A2 | Process for the preparation of o- and p-alkoxybenzaldehydes | HAARMANN & REIMER GMBH (DE) | 1987-02-04 | — | — | EP | disclosed |
| EP-0046307-B1 | NOVEL URACIL DERIVATIVES, PROCESS FOR PREPARING THE SAME AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-11-21 | — | — | EP | disclosed |
| US-4415573-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS; REACTING A 1,3-DIOXOLANE AND A URACIL USING AN ACID CATALYST AND SOLVENT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0046307-A1 | Novel uracil derivatives, process for preparing the same and a pharmaceutical composition containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176857-A1 | 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors | TBXA2R, P2RY4, PF4 | MAOA 559/4885KDM1A 3823/4885MAOB 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.