Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.86 |
| ▸ | CCKBR | P32239 | 1/20 | 0.67 |
| ▸ | TACR2 | P21452 | 5/20 | 0.63 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP14 | P50281 | 1/20 | 0.60 |
| ▸ | CDK4 | P11802 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200364 | 1.00 | TACR1 (0.86) | TACR1CCKBRTACR2MMP9MMP8 | |
| SCHEMBL1388788 | 0.88 | TACR1 (0.76) | TACR1CCKBRTACR2 | |
| SCHEMBL3780103 | 0.87 | MMP9 (0.77) | TACR1CCKBRMMP9MMP8MMP14 | |
| SCHEMBL8343099 | 0.87 | TACR1 (0.75) | TACR1CCKBRTACR2 | |
| SCHEMBL8343097 | 0.87 | TACR1 (0.75) | TACR1CCKBRTACR2 | |
| SCHEMBL6438893 | 0.85 | TACR1 (0.69) | TACR1CCKBRMMP9MMP8MMP14 | |
| SCHEMBL7193888 | 0.85 | TACR1 (0.69) | TACR1CCKBRMMP9MMP8MMP14 | |
| SCHEMBL9270140 | 0.84 | TACR1 (1.00) | TACR1CCKBRTACR2 | |
| SCHEMBL2680253 | 0.84 | MMP2 (0.72) | TACR1CCKBRMMP9MMP8MMP14 | |
| SCHEMBL26647227 | 0.83 | MMP9 (0.61) | TACR1MMP9MMP8MMP14ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000930-A2 | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 2000-05-17 | — | — | EP | claimed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | claimed |
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | claimed |
| WO-1994004494-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | claimed |
| EP-1000930-A2 | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004494-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |