Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198168 | 0.92 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL4045461 | 0.85 | KDM4E (0.46) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL3622667 | 0.84 | KDM4E (0.45) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL28455744 | 0.84 | ALOX15 (0.55) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL30995200 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL6448130 | 0.83 | RHEB (0.52) | HPGDKDM4ERHEB | |
| SCHEMBL7879695 | 0.82 | GABRA1 (0.48) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL703198 | 0.82 | KDM4E (0.58) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL28844724 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL700154 | 0.80 | KDM4E (0.51) | ALDH1A1HPGDKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071522-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS METHIONYL T-RNA SYNTHETASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | disclosed |