Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 8/20 | 0.70 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.63 |
| ▸ | PTGIR | P43119 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218770 | 0.88 | NISCH (0.61) | ALDH1A3NISCHPTGIRAPPKDM4E | |
| SCHEMBL8194609 | 0.88 | NISCH (0.61) | ALDH1A3NISCHAPPKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL8202383 | 0.81 | ALDH1A3 (0.46) | ALDH1A3NISCHAPPKDM4ENPC1 | |
| SCHEMBL9575256 | 0.79 | NISCH (1.00) | NISCHPTGIRKDM4E | |
| SCHEMBL8197701 | 0.79 | ALDH1A3 (0.44) | ALDH1A3NISCHAPPKDM4ENPC1 | |
| SCHEMBL13325773 | 0.79 | ALDH1A3 (1.00) | ALDH1A3APPKDM4ENPC1RAB9A | |
| SCHEMBL31380867 | 0.77 | ALDH1A3 (0.86) | ALDH1A3APPKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8202952 | 0.74 | NISCH (0.54) | ALDH1A3NISCHALDH1A1ALDH1A2SLC2A1 | |
| SCHEMBL8208826 | 0.74 | LMNA (0.48) | ALDH1A3NISCHAPPKDM4ENPC1 | |
| SCHEMBL2932154 | 0.74 | ALDH1A3 (0.79) | ALDH1A3APPKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |