Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.79 |
| ▸ | NPC1 | O15118 | 10/20 | 0.75 |
| ▸ | RAB9A | P51151 | 10/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.75 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | MITF | O75030 | 1/20 | 0.75 |
| ▸ | KDM5A | P29375 | 1/20 | 0.75 |
| ▸ | KDM5C | P41229 | 1/20 | 0.75 |
| ▸ | PKM | P14618 | 4/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325701 | 0.90 | ALDH1A3 (0.74) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL396368 | 0.86 | NPC1 (1.00) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13217828 | 0.84 | ALDH1A3 (0.75) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13198289 | 0.84 | ALDH1A3 (0.75) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL12380446 | 0.84 | ALDH1A3 (0.75) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2901138 | 0.84 | ALDH1A3 (0.75) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19322163 | 0.83 | ALDH1A3 (0.64) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13325773 | 0.83 | ALDH1A3 (1.00) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2193909 | 0.83 | NPC1 (0.65) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL13325749 | 0.82 | ALDH1A3 (0.71) | ALDH1A3NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | UNIV DE VELENCIA (ES) | 2026-03-12 | — | — | US | claimed |
| WO-2025003545-A1 | DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY | UNIVERSITAT DE VALÈNCIA (ES) | 2025-01-02 | — | — | WO | claimed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | claimed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | claimed |
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | UNIV DE VELENCIA (ES) | 2026-03-12 | — | — | US | disclosed |
| WO-2025003545-A1 | DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY | UNIVERSITAT DE VALÈNCIA (ES) | 2025-01-02 | — | — | WO | disclosed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-1682549-B1 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | SEPRACOR INC (US) | 2010-09-22 | — | — | EP | disclosed |
| EP-1682549-B1 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | SEPRACOR INC (US) | 2010-09-22 | — | — | EP | disclosed |
| US-20080096867-A1 | Imidazo[1,2-A] Pyridine Anxiolytics | SEPRACOR INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-20070043074-A1 | IMIDAZO[1,2-A] PYRIDINE ANXIOLYTICS | SEPRACOR INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-20070043074-A1 | IMIDAZO[1,2-A] PYRIDINE ANXIOLYTICS | SEPRACOR INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-20070043074-A1 | IMIDAZO[1,2-A] PYRIDINE ANXIOLYTICS | SEPRACOR INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-7148353-B2 | Imidazo[1,2-a] pyridine anxiolytics | SEPRACOR INC. (US) | 2006-12-12 | — | — | US | disclosed |
| EP-1682549-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | Sepracor Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20050171144-A1 | Imidazo[1,2-a] pyridine anxiolytics | SEPRACOR INC. (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005044818-A2 | IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS | SEPRACOR, INC. (US) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043074-A1 | IMIDAZO[1,2-A] PYRIDINE ANXIOLYTICS | CNR1, CNR2, GABRA5 | ALDH1A3 1311/4885NPC1 922/4885RAB9A 2233/4885 |
| US-20050171144-A1 | Imidazo[1,2-a] pyridine anxiolytics | CNR1, CNR2, GABRA5 | ALDH1A3 1311/4885NPC1 922/4885RAB9A 2233/4885 |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | DOT1L, NSD1, KDM3A | ALDH1A3 111/4885NPC1 4209/4885RAB9A 3350/4885 |
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | IL1A, IL6, IL1B | ALDH1A3 709/4885NPC1 933/4885RAB9A 1534/4885 |
| US-20080096867-A1 | Imidazo[1,2-A] Pyridine Anxiolytics | MTNR1B, ADORA2B, ADRA2B | ALDH1A3 1425/4885NPC1 1038/4885RAB9A 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.