Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AOC2 | O75106 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672968 | 0.77 | IDO1 (0.48) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL7859899 | 0.76 | ESR1 (0.59) | TAAR1PTGS1PTGS2L3MBTL1 | |
| SCHEMBL2553227 | 0.76 | — | — | |
| SCHEMBL12401864 | 0.76 | CHKA (0.41) | TAAR1PTGS1L3MBTL1 | |
| SCHEMBL2561988 | 0.76 | TAAR1 (0.50) | TAAR1MAOBIDO1MAOA | |
| SCHEMBL2560685 | 0.76 | TAAR1 (0.50) | TAAR1MAOBIDO1AOC3AGXT | |
| SCHEMBL7437052 | 0.76 | TAAR1 (0.68) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL1461571 | 0.75 | ALDH1A1 (0.48) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL990098 | 0.72 | TAAR1 (0.56) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL3893360 | 0.71 | DAO (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-6107274-A | ENZYME INHIBITORS AS HYPOGLYCEMIC AGENTS IN TREATMENT OF TYPE-II DIABETES | ONTOGEN CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |