SCHEMBL1461571

SCHEMBL1461571

[C-]#[N+]CCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TAAR1 Q96RJ0 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP2A6 P11509 1/20 0.46
HTR2A P28223 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
MAOA P21397 4/20 0.42
MAOB P27338 4/20 0.42
CALM1 P0DP23 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
ATM Q13315 1/20 0.41
KEAP1 Q14145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952463 0.85 SIGMAR1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL29957284 0.83 MAOA (0.52) HTR2AMAOAMAOBSIGMAR1
SCHEMBL7861391 0.81 LTA4H (0.58) SMN1; SMN2MAOAMAOBLMNACYP1A2
SCHEMBL7861390 0.80 TSHR (0.50) LMNACYP1A2IDO1TSHRPTGS1
SCHEMBL9863713 0.78 ALDH1A1 (0.52) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL2560685 0.75 TAAR1 (0.50) ALOX15TAAR1CYP2A6MAOBLMNA
SCHEMBL2561988 0.75 TAAR1 (0.50) TAAR1CYP2A6HTR2AMAOAMAOB
SCHEMBL12401864 0.75 CHKA (0.41) ALDH1A1TAAR1TDP1CA1CA2
SCHEMBL8200883 0.75 TAAR1 (0.50) TAAR1LOXL2MAOAMAOBIDO1
SCHEMBL2553227 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751360-A 1-Amide-1, 2-dihydro phthalazine compound and preparation method and application thereof 河南警察学院 2025-04-04 CN claimed
EP-3269724-B1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP claimed
EP-3118205-B1 MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP claimed
US-9884316-B2 Mononuclear ruthenium complex and organic synthesis reaction using same KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-02-06 US claimed
CN-107593739-A A kind of bactericidal composition and purposes containing Propineb and triazolone 利民化工股份有限公司 2018-01-19 CN claimed
US-20250308994-A1 SMALL MOLECULES FOR SELECTIVE DEPOSITION INTEL CORPORATION 2025-10-02 US disclosed
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2025-05-13 US disclosed
CN-119751360-A 1-Amide-1, 2-dihydro phthalazine compound and preparation method and application thereof 河南警察学院 2025-04-04 CN disclosed
EP-3184172-B1 HYDROSILYLATION IRON CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-09-04 EP disclosed
EP-3195932-B1 HYDROSILYLATION REACTION CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-08-21 EP disclosed
EP-3323505-B1 HYDROSILYLATION REACTION CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-07-17 EP disclosed
CN-117486844-A Green synthesis method of photo-promoted quaternary carbon center-containing phthalide derivative 重庆医科大学 2024-02-02 CN disclosed
US-4508694-A Separation and recovery of carbon monoxide by copper (I) complexes EXXON RESEARCH & ENGINEERING CO. (US) 1985-04-02 US disclosed
EP-0070638-B1 COPPER OR SILVER COMPLEXES WITH FLUORINATED DIKETONATES AND UNSATURATED HYDROCARBONS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-03-20 EP disclosed
EP-0125110-A1 Separation and recovery of carbon monoxide and unsaturated hydrocarbons by copper (I) complexes EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-11-14 EP disclosed
US-4434317-A Separation and recovery of unsaturated hydrocarbons by copper (I) complexes EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-02-28 US disclosed
US-4425281-A Copper or silver complexes with fluorinated diketones and unsaturated ligands EXXON RESEARCH AND ENGINEERING CO. (US) 1984-01-10 US disclosed
US-4385005-A Process for separating unsaturated hydrocarbons using copper or silver complexes with fluorinated diketonates EXXON RESEARCH AND ENGINEERING CO. (US) 1983-05-24 US disclosed
EP-0070638-A1 Copper or silver complexes with fluorinated diketonates and unsaturated hydrocarbons EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-26 EP disclosed
US-4232951-A DISPLAY DEVICE FOR MEMORY OR TEMPERATURE FUNCTIONS ALLIED CHEMICAL CORPORATION (US) 1980-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction H1-0, HVCN1, H1-2 ALDH1A1 1437/4885HPGD 547/4885ALOX15 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.