Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.56 |
| ▸ | IL1RN | P18510 | 4/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | NMBR | P28336 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200511 | 0.94 | KDM4E (0.51) | ERAP2ERAP1IL1RNGAAECE1 | |
| SCHEMBL8200899 | 0.85 | ERAP1 (0.67) | ERAP2ERAP1IL1RNLNPEPTACR1 | |
| SCHEMBL7313675 | 0.85 | ECE1 (0.61) | ERAP2ERAP1IL1RNECE1 | |
| SCHEMBL8210882 | 0.79 | ECE1 (0.52) | ERAP2ERAP1GAAECE1 | |
| SCHEMBL7304271 | 0.79 | ERAP2 (0.51) | ERAP2ERAP1IL1RNECE1 | |
| SCHEMBL7313702 | 0.78 | ECE1 (0.61) | ERAP2ERAP1IL1RNECE1 | |
| SCHEMBL7310121 | 0.76 | ERAP1 (0.63) | ERAP2ERAP1IL1RNLNPEPECE1 | |
| SCHEMBL27435445 | 0.75 | IL1RN (0.55) | ERAP2ERAP1IL1RNMAPTECE1 | |
| SCHEMBL27435446 | 0.75 | IL1RN (0.55) | ERAP2ERAP1IL1RNMAPTECE1 | |
| SCHEMBL27458142 | 0.75 | ERAP2 (0.67) | ERAP2ERAP1IL1RNLNPEPTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675890-B1 | CONDENSED BENZO(D)ISOXAZOLE DERIVATIVES AND THEIR USE AS PSYCHOACTIVE AGENTS | BRITISH TECH GROUP (GB) | 1997-04-09 | — | — | EP | disclosed |