SCHEMBL8200945

SCHEMBL8200945

CC(c1cn(S(=O)(=O)c2ccccc2)c2ccc(O)cc12)C1CCCN1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 19/20 0.47
KLK7 P49862 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8209521 0.88 HTR6 (0.51) HTR6
SCHEMBL8208533 0.88 HTR6 (0.57) HTR6
SCHEMBL8201606 0.86 HTR6 (0.45) HTR6
SCHEMBL8209777 0.85 HTR6 (0.53) HTR6
SCHEMBL8201465 0.83 HTR6 (0.43) HTR6
SCHEMBL8201528 0.80 HTR6 (0.50) HTR6
SCHEMBL8209795 0.80 HTR6 (0.49) HTR6KLK7
SCHEMBL7472995 0.80 HTR6 (0.48) HTR6KLK7
SCHEMBL8208598 0.79 HTR6 (0.48) HTR6
SCHEMBL8201576 0.78 HTR6 (0.63) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6100291-A FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS ALLELIX BIOPHARMACEUTICALS INC. (CA) 2000-08-08 US claimed
WO-1999047516-A1 3-(2-PYRROLIDINYLMETHYL)-INDOLE COMPOUNDS HAVING 5-HT6 AFFINITY SLASSI ABDELMALIK (CA) 1999-09-23 WO claimed
US-6100291-A FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS ALLELIX BIOPHARMACEUTICALS INC. (CA) 2000-08-08 US disclosed
WO-1999047516-A1 3-(2-PYRROLIDINYLMETHYL)-INDOLE COMPOUNDS HAVING 5-HT6 AFFINITY SLASSI ABDELMALIK (CA) 1999-09-23 WO disclosed