Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563351 | 0.84 | MMP9 (0.56) | MMP9MMP8MEN1KMT2AMMP2 | |
| SCHEMBL7856260 | 0.80 | MMP9 (0.52) | MMP9MMP8MEN1KMT2AMMP2 | |
| SCHEMBL6394945 | 0.79 | GPR84 (0.54) | MEN1KMT2ANOD2MGAMGAA | |
| SCHEMBL8201153 | 0.78 | MMP9 (0.80) | MMP9MMP8MEN1KMT2AMMP2 | |
| SCHEMBL8850370 | 0.78 | MMP9 (0.80) | MMP9MMP8MEN1KMT2AMMP2 | |
| SCHEMBL8201151 | 0.78 | MMP9 (0.80) | MMP9MMP8MEN1KMT2AMMP2 | |
| SCHEMBL7851600 | 0.76 | MEN1 (0.52) | MMP9MMP8MEN1KMT2AMMP2 | |
| SCHEMBL8700164 | 0.76 | ALOX15 (0.48) | MEN1KMT2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8711954 | 0.76 | ALOX15 (0.48) | MEN1KMT2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8573522 | 0.76 | GPR84 (0.50) | MEN1KMT2ACYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000930-A2 | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004494-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |