Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6395059 | 0.86 | LMNA (0.52) | LMNARECQLALDH1A1MAPTHTT | |
| SCHEMBL167129 | 0.86 | LMNA (0.52) | LMNARECQLALDH1A1MAPTHTT | |
| SCHEMBL9564637 | 0.82 | LMNA (0.68) | LMNARECQLALDH1A1MAPTHTT | |
| SCHEMBL551186 | 0.78 | LMNA (0.59) | LMNARECQLALDH1A1MAPTHTT | |
| SCHEMBL28824115 | 0.77 | LMNA (0.44) | LMNARECQLALDH1A1MAPTPPARG | |
| SCHEMBL8443744 | 0.77 | LMNA (0.57) | LMNARECQLALDH1A1MAPTHTT | |
| SCHEMBL11612204 | 0.77 | LMNA (0.57) | LMNARECQLALDH1A1MAPTHTT | |
| SCHEMBL26654140 | 0.77 | LMNA (0.49) | LMNARECQLALDH1A1MAPTHTT | |
| SCHEMBL9581012 | 0.74 | TRPA1 (0.37) | LMNARECQLALDH1A1MAPTPPARG | |
| SCHEMBL5729586 | 0.74 | ALDH1A1 (0.46) | LMNARECQLALDH1A1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6126930-A | REDUCING TRIGEMINAL STIMULATION FROM AN ATOMIZED ALCOHOL | THE PROCTER & GAMBLE COMPANY (US) | 2000-10-03 | — | — | US | disclosed |
| US-5972361-A | USEFUL FOR BOTH CLEANSING AND CONDITIONING THE SKIN OR HAIR; COMPRISINGWATER INSOLUBLE SUBSTRATE, LATHERING SURFACTANT, AND OIL SOLUBLE CONDITIONING AGENT | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-26 | — | — | US | disclosed |