Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702752 | 0.80 | PTGS2 (0.42) | ALDH1A1TDP1PTGS2LMNAMAPK1 | |
| SCHEMBL28647295 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TDP1PTGS2LMNAMAPK1 | |
| SCHEMBL1245561 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TDP1PTGS2LMNAMAPK1 | |
| SCHEMBL541122 | 0.76 | FFAR3 (0.31) | — | |
| SCHEMBL11477347 | 0.72 | PTGS2 (0.47) | ALDH1A1PTGS2LMNAMAPK1MAPT | |
| SCHEMBL19357468 | 0.70 | ALDH1A1 (0.47) | ALDH1A1PTGS2LMNAMAPK1MAPT | |
| SCHEMBL19357469 | 0.70 | ALDH1A1 (0.47) | ALDH1A1PTGS2LMNAMAPK1MAPT | |
| SCHEMBL3410010 | 0.70 | ALDH1A1 (0.50) | ALDH1A1PTGS2LMNAMEN1KMT2A | |
| SCHEMBL13389325 | 0.70 | ALDH1A1 (0.50) | ALDH1A1PTGS2LMNAMEN1KMT2A | |
| SCHEMBL29119412 | 0.69 | KDM4E (0.43) | ALDH1A1TDP1LMNAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |