Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551477 | 0.86 | HSD11B1 (0.48) | TBXAS1NAPRTHSD11B1LMNAKMT2A | |
| SCHEMBL361358 | 0.83 | NAPRT (0.61) | TBXAS1NAPRTHSD11B1LMNAKMT2A | |
| SCHEMBL10675204 | 0.83 | TBXAS1 (0.70) | TBXAS1NAPRTTDP1 | |
| Hydrochloric Acid SCHEMBL8017516 | 0.82 | NAPRT (0.59) | TBXAS1NAPRTHSD11B1LMNAKMT2A | |
| SCHEMBL508419 | 0.81 | TSHR (0.56) | LMNAKMT2ATDP1FFAR1MAPT | |
| SCHEMBL23748572 | 0.80 | PTAFR (0.54) | NAPRTHSD11B1LMNAKMT2ATDP1 | |
| SCHEMBL149174 | 0.80 | HSD11B1 (0.47) | NAPRTHSD11B1LMNAKMT2ATDP1 | |
| SCHEMBL146442 | 0.80 | HSD11B1 (0.47) | NAPRTHSD11B1KDM4ECYP1A2CYP17A1 | |
| SCHEMBL29469530 | 0.80 | HSD11B1 (0.47) | NAPRTHSD11B1KDM4ECYP1A2CYP17A1 | |
| SCHEMBL10615037 | 0.79 | TBXAS1 (0.56) | TBXAS1NAPRTLMNAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672678-B1 | Azapeptide derivative | FUJIREBIO KK (JP) | 2000-10-25 | — | — | EP | disclosed |
| US-5965538-A | FOR TREATING NERVOUS INFLAMMATION OF RESPIRATORY SYSTEMS, ASTHMA, BRONCHOSPASM | FUJIREBIO INC. (JP) | 1999-10-12 | — | — | US | disclosed |
| US-5837687-A | BRONCHODILATORS, ANTIHISTAMINES AND ANTIINFLAMMATORY AGENTS; ASTHMA; ANTAGONIST OF NEUROKININ RECEPTORS | FUJIREBIO INC. (JP) | 1998-11-17 | — | — | US | disclosed |
| EP-0672678-A1 | Azapeptide derivative | FUJIREBIO Inc. (JP) | 1995-09-20 | — | — | EP | disclosed |