Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP10 | P09238 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195427 | 0.89 | KDM4E (0.56) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL688481 | 0.89 | KDM4E (0.51) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8201664 | 0.88 | ALDH1A1 (0.53) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8202655 | 0.84 | CDC7 (0.38) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8198105 | 0.82 | SIRT5 (0.52) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8197637 | 0.81 | ALDH1A1 (0.63) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8190630 | 0.80 | ALDH1A1 (0.52) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL5062988 | 0.80 | KMT2A (0.55) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8188266 | 0.80 | ALDH1A1 (0.41) | KDM4EKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8188111 | 0.80 | TMIGD3 (0.59) | KDM4EKMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |