Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195427 | 0.89 | KDM4E (0.56) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL8198105 | 0.88 | SIRT5 (0.52) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL688686 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL8201203 | 0.88 | KDM4E (0.44) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL688766 | 0.86 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL8190630 | 0.84 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL8195420 | 0.84 | KMT2A (0.60) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL8197637 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL8188266 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL8188111 | 0.81 | TMIGD3 (0.59) | ALDH1A1KDM4EKMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |