Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 9/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 10/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 4/20 | 0.40 |
| ▸ | MMP12 | P39900 | 4/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399097 | 0.99 | MMP1 (0.52) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL7208693 | 0.88 | MMP1 (0.68) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL7213401 | 0.86 | MMP1 (0.66) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL20444027 | 0.80 | MMP1 (0.72) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL7207036 | 0.76 | MMP1 (0.74) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL7213028 | 0.76 | MMP1 (0.56) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL7212102 | 0.75 | MMP13 (0.80) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL7212751 | 0.73 | MMP13 (0.82) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL8340312 | 0.73 | MMP1 (0.65) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL25001332 | 0.72 | MMP1 (0.62) | MMP1MMP3MMP2MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013649-A | BOND DISORDERS; AUTOIMMUNE DISEASES; ANTITUMOR AGENTS | MONSANTO COMPANY (US) | 2000-01-11 | — | — | US | disclosed |