Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.65 |
| ▸ | MMP2 | P08253 | 8/20 | 0.65 |
| ▸ | MMP3 | P08254 | 7/20 | 0.65 |
| ▸ | MMP13 | P45452 | 8/20 | 0.58 |
| ▸ | MMP9 | P14780 | 6/20 | 0.58 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.58 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20444027 | 0.88 | MMP1 (0.72) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7208693 | 0.84 | MMP1 (0.68) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7213401 | 0.83 | MMP1 (0.66) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7212102 | 0.82 | MMP13 (0.80) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7212751 | 0.80 | MMP13 (0.82) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7207044 | 0.80 | MMP1 (0.76) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7064773 | 0.79 | MMP1 (1.00) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7346604 | 0.76 | MMP13 (0.75) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL6928909 | 0.76 | MMP13 (0.75) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL13043584 | 0.76 | MMP1 (0.85) | MMP1MMP2MMP3MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |