Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196703 | 0.90 | PTGS2 (0.42) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| SCHEMBL8194868 | 0.90 | PTGS2 (0.44) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| SCHEMBL8196960 | 0.90 | PTGS2 (0.40) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| SCHEMBL8196083 | 0.89 | ALDH1A1 (0.40) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| SCHEMBL8194835 | 0.89 | PTGS2 (0.41) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| SCHEMBL8195559 | 0.89 | POLB (0.40) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| SCHEMBL8187629 | 0.88 | PTGS2 (0.41) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL8199133 | 0.88 | PTGS2 (0.39) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| SCHEMBL8200043 | 0.87 | PTGS2 (0.40) | PTGS2PTGS1ALDH1A1LMNARAB9A | |
| SCHEMBL8201204 | 0.86 | PTGS2 (0.39) | PTGS2PTGS1ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018741-A2 | PYRAZOLE COMPOUNDS AS COX-2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-06 | — | — | WO | disclosed |