Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528965 | 0.76 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL29783340 | 0.70 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1HPGDPIN1 | |
| SCHEMBL20717240 | 0.70 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1HPGDPIN1 | |
| SCHEMBL8089749 | 0.67 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL15265352 | 0.65 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11453331 | 0.63 | ALDH1A1 (0.77) | L3MBTL1ALDH1A1KMT2AMEN1PIN1 | |
| SCHEMBL12471113 | 0.63 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL3785359 | 0.62 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL3777633 | 0.62 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL30862418 | 0.62 | ADORA3 (0.54) | L3MBTL1ALDH1A1KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682030-B1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| EP-0647644-B1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0682030-A1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0647644-A1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |