Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585434 | 0.94 | CTNNB1 (0.44) | THRATHRBCTNNB1WNT3ARECQL | |
| SCHEMBL8205873 | 0.85 | PPARA (0.44) | PTPN11PDE4BPPARGPPARAPDE4D | |
| SCHEMBL2587585 | 0.79 | SELP (0.47) | PPARGPPARARECQLPDE4DL3MBTL1 | |
| SCHEMBL27917457 | 0.77 | SLC6A4 (0.38) | RECQLL3MBTL1 | |
| SCHEMBL8710187 | 0.77 | PPARA (0.52) | PTPN11PPARGPPARA | |
| SCHEMBL2592720 | 0.77 | HTR7 (0.56) | PPARGL3MBTL1 | |
| SCHEMBL8333162 | 0.76 | PTPN11 (0.46) | PTPN11PPARGPPARA | |
| SCHEMBL8200551 | 0.73 | PPARA (0.44) | THRATHRBPTPN11PPARGPPARA | |
| SCHEMBL8339408 | 0.72 | HTR7 (0.41) | PPARGRECQLL3MBTL1 | |
| SCHEMBL8193447 | 0.72 | P4HB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840606-B1 | DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS | TEXAS BIOTECHNOLOGY CORP (US) | 2000-06-07 | — | — | EP | disclosed |
| US-5919768-A | COMPOUNDS WHICH INHIBIT BINDING OF SELECTINS TO SIALYL-LEWIS-X AND SIALYL-LEWIS-A CARBOHYDRATES | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0840606-A1 | DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-05-13 | — | — | EP | disclosed |
| EP-0840606-A4 | — | — | 1998-05-13 | — | — | EP | disclosed |
| WO-1997001335-A1 | DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1997-01-16 | — | — | WO | disclosed |