Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | SELP | P16109 | 2/20 | 0.44 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587585 | 0.95 | SELP (0.47) | PPARAPPARGSELPSELPLGPDE4D | |
| SCHEMBL8710187 | 0.92 | PPARA (0.52) | PPARAPPARGSELPSELPLGPTPN11 | |
| SCHEMBL8200551 | 0.88 | PPARA (0.44) | PPARAPPARGSELPSELPLGL3MBTL1 | |
| SCHEMBL8201339 | 0.85 | THRA (0.43) | PPARAPPARGPDE4APDE4BPDE4C | |
| SCHEMBL8200129 | 0.84 | JAK2 (0.49) | SELPSELPLGPDE4APDE4BPDE4C | |
| SCHEMBL2589280 | 0.82 | PPARA (0.48) | PPARAPPARGSELPSELPLGL3MBTL1 | |
| SCHEMBL8206180 | 0.81 | SELP (0.73) | PPARAPPARGSELPSELPLG | |
| SCHEMBL8206178 | 0.81 | SELP (0.73) | PPARAPPARGSELPSELPLG | |
| SCHEMBL2592720 | 0.79 | HTR7 (0.56) | PPARGSELPL3MBTL1ALOX5NPC1 | |
| SCHEMBL8333162 | 0.79 | PTPN11 (0.46) | PPARAPPARGPTPN11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840606-B1 | DI- AND TRIVALENT SMALL MOLECULE SELECTIN INHIBITORS | TEXAS BIOTECHNOLOGY CORP (US) | 2000-06-07 | — | — | EP | disclosed |